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    rbm-17 Splicing factor 45 [ Caenorhabditis elegans ]

    Gene ID: 178091, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rbm-17
    Official Full Name
    Splicing factor 45
    Primary source
    WormBase:WBGene00010233
    Locus tag
    CELE_F58B3.7
    See related
    AllianceGenome:WB:WBGene00010233
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Orthologous to human RBM17 (RNA binding motif protein 17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rbm-17 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (11638316..11640097)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Methionine--tRNA ligase, cytoplasmic;tRNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene Interferon-related developmental regulator N-terminal domain-containing protein Neighboring gene Transthyretin-like family protein Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene Cardiac phospholamban

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii. Dendouga N, et al. Eur J Biochem, 2002 Jul. PMID 12135477
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA cis splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Splicing factor 45
    NP_502198.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11638316..11640097
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069797.7 → NP_502198.1  Splicing factor 45 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502198.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20966
      Conserved Domains (2) summary
      cd12374
      Location:273 → 362
      RRM_UHM_SPF45_PUF60; RNA recognition motif in UHM domain of 45 kDa-splicing factor (SPF45) and similar proteins
      pfam01585
      Location:211 → 254
      G-patch; G-patch domain
    Nucleotide Protein
    Heading Accession and Version

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