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    abu-6 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

    Gene ID: 178903, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abu-6
    Official Full Name
    Activated in Blocked Unfolded protein response
    Primary source
    WormBase:WBGene00000029
    Locus tag
    CELE_C03A7.7
    See related
    AllianceGenome:WB:WBGene00000029
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in pharynx development. Is expressed in pharyngeal muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abu-6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (5160678..5161892, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene ncRNA Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. George-Raizen JB, et al. Biol Open, 2014 Oct 31. PMID 25361578, Free PMC Article
    2. Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Haskins KA, et al. Dev Cell, 2008 Jul. PMID 18606143, Free PMC Article
    3. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan M, et al. Dev Cell, 2005 Nov. PMID 16256736
    4. Muscle-epidermis interactions affect exoskeleton patterning in Caenorhabditis elegans. Broday L, et al. Dev Dyn, 2007 Nov. PMID 17937397
    5. A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. Urano F, et al. J Cell Biol, 2002 Aug 19. PMID 12186849, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
    involved_in endoplasmic reticulum unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pharynx development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Activated in Blocked Unfolded protein response
    NP_504383.1
    • Product from WormBase gene class abu;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5160678..5161892 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071982.6 → NP_504383.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504383.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16501
    Nucleotide Protein
    Heading Accession and Version

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