W09D10.4 Protein phosphatase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: W09D10.4
Official Full Name: Protein phosphatase
Primary source: WormBase:WBGene00012362
Locus tag: CELE_W09D10.4
See related: AllianceGenome:WB:WBGene00012362
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in regulation of ubiquinone biosynthetic process. Predicted to be active in mitochondrion. Orthologous to human PPTC7 (protein phosphatase targeting COQ7). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See W09D10.4 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (10711530..10716191, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor.
Title: Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W09D10.4 (e-PCR)
- UniSTS:320379

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables myosin phosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphoprotein phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Protein phosphatase

NP_499362.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

10711530..10716191 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066961.6 → NP_499362.1 Protein phosphatase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499362.1

Status: REVIEWED

UniProtKB/TrEMBL

O18183

Conserved Domains (1) summary

smart00332
Location:72 → 327

PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain