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    pqn-41 Polyglutamine-repeat protein pqn-41 [ Caenorhabditis elegans ]

    Gene ID: 175335, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pqn-41
    Official Full Name
    Polyglutamine-repeat protein pqn-41
    Primary source
    WormBase:WBGene00004128
    Locus tag
    CELE_F53A3.4
    See related
    AllianceGenome:WB:WBGene00004128
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in cytoplasm. Is expressed widely. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pqn-41 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    24
    Sequence:
    Chromosome: III; NC_003281.10 (1905958..1939569)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene PNPLA domain-containing protein Neighboring gene HMG box domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene MARVEL domain-containing protein Neighboring gene DNA polymerase eta Neighboring gene Ribosomal Protein, Small subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PolyQ disease: misfiring of a developmental cell death program? Blum ES, et al. Trends Cell Biol, 2013 Apr. PMID 23228508, Free PMC Article
    2. Development. Cell death by glutamine repeats? Link CD, et al. Science, 2012 Feb 24. PMID 22362996
    3. TDP-1 and FUST-1 co-inhibit exon inclusion and control fertility together with transcriptional regulation. Taylor M, et al. Nucleic Acids Res, 2023 Oct 13. PMID 37587694, Free PMC Article
    4. Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway. Bounoutas A, et al. Proc Natl Acad Sci U S A, 2011 Mar 8. PMID 21368137, Free PMC Article
    5. Control of nonapoptotic developmental cell death in Caenorhabditis elegans by a polyglutamine-repeat protein. Blum ES, et al. Science, 2012 Feb 24. PMID 22363008, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Polyglutamine-repeat protein pqn-41
    NP_001122699.2
    • Confirmed by transcript evidence
    NP_001254849.1
    • Partially confirmed by transcript evidence
    NP_001360184.1
    • Confirmed by transcript evidence
    NP_497478.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1905958..1939569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065077.6 → NP_497478.2  Polyglutamine-repeat protein pqn-41 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497478.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C7IVR4

    2. NM_001129227.4 → NP_001122699.2  Polyglutamine-repeat protein pqn-41 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122699.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C7IVR4, C7IVR5, C7IVR6, G4RT56, G4RT57, G4RT58, S6FMX9

    3. NM_001267920.3 → NP_001254849.1  Polyglutamine-repeat protein pqn-41 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254849.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C7IVR4

    4. NM_001373851.2 → NP_001360184.1  Polyglutamine-repeat protein pqn-41 [Caenorhabditis elegans]

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    C7IVR4.2

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