U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    perm-3 ER membrane protein complex subunit 4 [ Caenorhabditis elegans ]

    Gene ID: 177324, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    perm-3
    Official Full Name
    ER membrane protein complex subunit 4
    Primary source
    WormBase:WBGene00022776
    Locus tag
    CELE_ZK616.6
    See related
    AllianceGenome:WB:WBGene00022776
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Orthologous to human EMC4 (ER membrane protein complex subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See perm-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (5393843..5394804, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene HORMA domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Actin-related protein 4 Neighboring gene CHCH domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Degenerin similarities. Chalfie M, et al. Nature, 1993 Feb 11. PMID 8429902
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ER membrane protein complex subunit 4
    NP_001368428.1
    • Confirmed by transcript evidence
    NP_500802.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5393843..5394804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068401.8 → NP_500802.1  ER membrane protein complex subunit 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500802.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4N3
      Conserved Domains (1) summary
      pfam06417
      Location:45 → 159
      DUF1077; Protein of unknown function (DUF1077)

    2. NM_001380228.1 → NP_001368428.1  ER membrane protein complex subunit 4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CM14
      Conserved Domains (1) summary
      pfam06417
      Location:1 → 98
      DUF1077; Protein of unknown function (DUF1077)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools