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    gldr-2 PAP-associated domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173373, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gldr-2
    Official Full Name
    PAP-associated domain-containing protein
    Primary source
    WormBase:WBGene00009284
    Locus tag
    CELE_F31C3.2
    See related
    AllianceGenome:WB:WBGene00009284
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in RNA 3'-end processing. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gldr-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    11
    Sequence:
    Chromosome: I; NC_003279.8 (15036009..15040537)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene TPT domain-containing protein Neighboring gene Acidic leucine-rich nuclear phosphoprotein 32-related protein 1 Neighboring gene Peptidyl-prolyl cis-trans isomerase 5 Neighboring gene FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Zrt (ZRT), Irt- (IRT-) like Protein Transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A family of poly(U) polymerases. Kwak JE, et al. RNA, 2007 Jun. PMID 17449726, Free PMC Article
    2. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Lehrbach NJ, et al. Nat Struct Mol Biol, 2009 Oct. PMID 19713957, Free PMC Article
    3. Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components. Tarailo M, et al. Genetics, 2007 Dec. PMID 18073444, Free PMC Article
    4. Screening by deep sequencing reveals mediators of microRNA tailing in C. elegans. Vieux KF, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34586415, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables poly(A) RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PAP-associated domain-containing protein
    NP_001021433.1
    • Confirmed by transcript evidence
    NP_001021434.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      15036009..15040537
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026263.4 → NP_001021434.1  PAP-associated domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021434.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFR3
      Conserved Domains (1) summary
      COG5260
      Location:483 → 799
      TRF4; DNA polymerase sigma [Replication, recombination and repair]

    2. NM_001026262.7 → NP_001021433.1  PAP-associated domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021433.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFM8
      Conserved Domains (1) summary
      COG5260
      Location:480 → 796
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version

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