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    nlp-8 SFDRMGGTEFGLM [ Caenorhabditis elegans ]

    Gene ID: 172544, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nlp-8
    Official Full Name
    SFDRMGGTEFGLM
    Primary source
    WormBase:WBGene00003746
    Locus tag
    CELE_D2005.2
    See related
    AllianceGenome:WB:WBGene00003746
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in sleep. Predicted to be located in extracellular region. Is expressed in intestine; neurons; and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nlp-8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (7800455..7801822, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene MARVEL domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene TPR_REGION domain-containing protein Neighboring gene NAM-associated domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deciphering the Role of EGL-3 for Neuropeptides Processing in Caenorhabditis elegans Using High-Resolution Quadrupole-Orbitrap Mass Spectrometry. Salem JB, et al. Neurochem Res, 2018 Nov. PMID 30229400
    2. The actions of Caenorhabditis elegans neuropeptide-like peptides (NLPs) on body wall muscle of Ascaris suum and pharyngeal muscle of C. elegans. Papaioannou S, et al. Acta Biol Hung, 2008. PMID 18652392
    3. C. elegans Stress-Induced Sleep Emerges from the Collective Action of Multiple Neuropeptides. Nath RD, et al. Curr Biol, 2016 Sep 26. PMID 27546573, Free PMC Article
    4. Caenorhabditis elegans inositol 5-phosphatase homolog negatively regulates inositol 1,4,5-triphosphate signaling in ovulation. Bui YK, et al. Mol Biol Cell, 2002 May. PMID 12006659, Free PMC Article
    5. Distinct roles of transcription factors EGL-46 and DAF-19 in specifying the functionality of a polycystin-expressing sensory neuron necessary for C. elegans male vulva location behavior. Yu H, et al. Development, 2003 Nov. PMID 12954713

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sleep IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SFDRMGGTEFGLM
    NP_492158.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7800455..7801822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059757.8 → NP_492158.1  SFDRMGGTEFGLM [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492158.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93409
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93409.1

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