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    K07E8.6 Cdc37 Hsp90 binding domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187114, updated on 9-Dec-2024

    Summary

    Official Symbol
    K07E8.6
    Official Full Name
    Cdc37 Hsp90 binding domain-containing protein
    Primary source
    WormBase:WBGene00019497
    Locus tag
    CELE_K07E8.6
    See related
    AllianceGenome:WB:WBGene00019497
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable heat shock protein binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and protein stabilization. Predicted to be active in cytoplasm. Orthologous to human CDC37L1 (cell division cycle 37 like 1, HSP90 cochaperone) and CDC37 (cell division cycle 37, HSP90 cochaperone). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See K07E8.6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (637318..639567, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Pseudouridine synthase Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heat shock protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Cdc37 Hsp90 binding domain-containing protein
    NP_001254017.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      637318..639567 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267088.3NP_001254017.1  Cdc37 Hsp90 binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254017.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0F2
      Conserved Domains (1) summary
      cl07248
      Location:78197
      CDC37_M; Cdc37 Hsp90 binding domain

    RNA

    1. NR_133627.1 RNA Sequence

      Status: REVIEWED