egal-1 Egalitarian protein homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: egal-1
Official Full Name: Egalitarian protein homolog
Primary source: WormBase:WBGene00015680
Locus tag: CELE_C10G6.1
See related: AllianceGenome:WB:WBGene00015680
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 3'-5' exonuclease activity and nucleic acid binding activity. Predicted to be involved in piRNA processing. Predicted to be located in nuclear envelope. Predicted to be part of PET complex. Orthologous to human EXD1 (exonuclease 3'-5' domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See egal-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 6

Sequence:: Chromosome: IV; NC_003282.8 (5824793..5830200)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C10G6.1 (e-PCR)
- UniSTS:308531

STS4-132 (e-PCR)
- UniSTS:242121

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 3'-5' exonuclease activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in nucleobase-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
involved_in piRNA processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of PET complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear envelope	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Egalitarian protein homolog

NP_001021323.1

Confirmed by transcript evidence

NP_001021324.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

5824793..5830200

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001026153.3 → NP_001021324.1 Egalitarian protein homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001021324.1

Status: REVIEWED

UniProtKB/TrEMBL

Q65ZH5

Conserved Domains (1) summary

cd06148
Location:309 → 501

Egl_like_exo; DEDDy 3'-5' exonuclease domain of Drosophila Egalitarian (Egl) and similar proteins
NM_001026152.6 → NP_001021323.1 Egalitarian protein homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001021323.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q17902, Q65ZH5

Conserved Domains (1) summary

cd06148
Location:309 → 503

Egl_like_exo; DEDDy 3'-5' exonuclease domain of Drosophila Egalitarian (Egl) and similar proteins