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    dylt-2 Tctex1 domain-containing protein 2 [ Caenorhabditis elegans ]

    Gene ID: 183892, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dylt-2
    Official Full Name
    Tctex1 domain-containing protein 2
    Primary source
    WormBase:WBGene00017014
    Locus tag
    CELE_D1009.5
    See related
    AllianceGenome:WB:WBGene00017014
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Located in axoneme. Is expressed in nervous system. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNLT2B (dynein light chain Tctex-type 2B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dylt-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (8939220..8940159, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene tRNA-Gln Neighboring gene ncRNA Neighboring gene Long-chain-fatty-acid--CoA ligase Neighboring gene tRNA-Leu Neighboring gene Protein kinase domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Trp Neighboring gene ncRNA Neighboring gene tRNA-Trp

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The retrograde IFT machinery of C. elegans cilia: two IFT dynein complexes? Hao L, et al. PLoS One, 2011. PMID 21695221, Free PMC Article
    2. Actin-dependent cytoplasmic streaming in C. elegans oogenesis. Wolke U, et al. Development, 2007 Jun. PMID 17507392
    3. Analysis of xbx genes in C. elegans. Efimenko E, et al. Development, 2005 Apr. PMID 15790967
    4. The sensory cilia of Caenorhabditis elegans. Inglis PN, et al. WormBook, 2007 Mar 8. PMID 18050505, Free PMC Article
    5. Functional genomics of the cilium, a sensory organelle. Blacque OE, et al. Curr Biol, 2005 May 24. PMID 15916950

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in axoneme IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytoplasmic dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Tctex1 domain-containing protein 2
    NP_509511.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8939220..8940159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077110.3 → NP_509511.1  Tctex1 domain-containing protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509511.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18917
    Nucleotide Protein
    Heading Accession and Version

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