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    clec-67 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177151, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-67
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00018971
    Locus tag
    CELE_F56D6.2
    See related
    AllianceGenome:WB:WBGene00018971
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in PERK-mediated unfolded protein response. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-67 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    9
    Sequence:
    Chromosome: IV; NC_003282.8 (3922165..3924515)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Serpentine Receptor, class Z Neighboring gene C-type lectin domain-containing protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans. Cornejo Castro EM, et al. J Neural Transm (Vienna), 2010 May. PMID 20376509
    2. Innate immune genes including a mucin-like gene, mul-1, induced by ionizing radiation in Caenorhabditis elegans. Kimura T, et al. Radiat Res, 2012 Oct. PMID 22967128
    3. Modulatory upregulation of an insulin peptide gene by different pathogens in C. elegans. Lee SH, et al. Virulence, 2018 Dec 31. PMID 29405821, Free PMC Article
    4. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. Lo Sasso G, et al. PLoS One, 2014. PMID 25013930, Free PMC Article
    5. A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Reddy KC, et al. Science, 2009 Jan 16. PMID 19150845, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in PERK-mediated unfolded protein response HEP PubMed 

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein
    NP_500437.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3922165..3924515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068036.7 → NP_500437.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500437.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ITX4
      Conserved Domains (1) summary
      pfam00059
      Location:39 → 145
      Lectin_C; Lectin C-type domain
    Nucleotide Protein
    Heading Accession and Version

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