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    dod-17 CUB-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187266, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dod-17
    Official Full Name
    CUB-like domain-containing protein
    Primary source
    WormBase:WBGene00010745
    Locus tag
    CELE_K10D11.1
    See related
    AllianceGenome:WB:WBGene00010745
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dod-17 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (12976303..12978343)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene CUB-like domain-containing protein Neighboring gene ncRNA Neighboring gene CUB-like domain-containing protein Neighboring gene CUB-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction. Huayta J, et al. Commun Biol, 2023 Feb 20. PMID 36807646, Free PMC Article
    2. ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia. Mahapatra A, et al. PLoS Biol, 2023 Sep. PMID 37747897, Free PMC Article
    3. Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure. Boyd WA, et al. Mutat Res, 2010 Jan 5. PMID 19879883, Free PMC Article
    4. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Murphy CT, et al. Nature, 2003 Jul 17. PMID 12845331
    5. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CUB-like domain-containing protein
    NP_502486.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12976303..12978343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070085.7 → NP_502486.2  CUB-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502486.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45667
      Conserved Domains (1) summary
      pfam02408
      Location:17 → 135
      CUB_2; CUB-like domain
    Nucleotide Protein
    Heading Accession and Version

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