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    dpy-14 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172410, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpy-14
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00001075
    Locus tag
    CELE_H27M09.4
    See related
    AllianceGenome:WB:WBGene00001075
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Is expressed in anterior ganglion; hypodermis; and lateral ganglion left neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dpy-14 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (6843589..6845142)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Adenosylhomocysteinase Neighboring gene Dipeptidyl Peptidase Four (IV) family Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans dpy-14: an essential collagen gene with unique expression profile and physiological roles in early development. Gallo M, et al. Mol Genet Genomics, 2006 Jun. PMID 16496175
    2. Somatic excision of transposable element Tc1 from the Bristol genome of Caenorhabditis elegans. Harris LJ, et al. Mol Cell Biol, 1986 May. PMID 3023903, Free PMC Article
    3. Toxic Effects of Size-tunable Gold Nanoparticles on Caenorhabditis elegans Development and Gene Regulation. Hu CC, et al. Sci Rep, 2018 Oct 15. PMID 30323250, Free PMC Article
    4. Molecular characterization in the dpy-14 region identifies the adenosylhomocysteine hydrolase gene in Caenorhabditis elegans. Prasad SS, et al. Genome, 1993 Feb. PMID 8458573
    5. The effect of gamma radiation on recombination frequency in Caenorhabditis elegans. Kim JS, et al. Genome, 1987 Jun. PMID 3609740

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_491958.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6843589..6845142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059557.7 → NP_491958.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491958.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEB6
      Conserved Domains (2) summary
      pfam01391
      Location:180 → 223
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:20 → 64
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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