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    nduf-5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [ Caenorhabditis elegans ]

    Gene ID: 266824, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nduf-5
    Official Full Name
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
    Primary source
    WormBase:WBGene00021839
    Locus tag
    CELE_Y54E10BL.5
    See related
    AllianceGenome:WB:WBGene00021839
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nduf-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (3001406..3002847, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SUPpressor of Rpm-1 Neighboring gene J domain-containing protein Neighboring gene CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone Neighboring gene Dual specificity mitogen-activated protein kinase kinase mek-2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of mitochondria in the life of the nematode, Caenorhabditis elegans. Tsang WY, et al. Biochim Biophys Acta, 2003 Jul 14. PMID 12853115
    2. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of respiratory chain complex I ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
    NP_491085.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3001406..3002847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058684.8 → NP_491085.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491085.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3D9
      Conserved Domains (1) summary
      pfam10200
      Location:37 → 99
      Ndufs5; NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
    Nucleotide Protein
    Heading Accession and Version

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