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    T22C1.6 Transport and Golgi organization protein 1 homolog [ Caenorhabditis elegans ]

    Gene ID: 172568, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T22C1.6
    Official Full Name
    Transport and Golgi organization protein 1 homolog
    Primary source
    WormBase:WBGene00011917
    Locus tag
    CELE_T22C1.6
    See related
    AllianceGenome:WB:WBGene00011917
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable syntaxin binding activity. Located in endoplasmic reticulum. Is expressed in several structures, including body wall musculature; head; non-striated muscle; pharynx; and tail. Orthologous to human TXLNA (taxilin alpha); TXLNB (taxilin beta); and TXLNG (taxilin gamma). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T22C1.6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (7942719..7945551)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene GPI transamidase component GAB1 Neighboring gene Ctf8 Neighboring gene TFIIIC_sub6 domain-containing protein Neighboring gene Junctophilin-1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    Transport and Golgi organization protein 1 homolog
    NP_001379147.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7942719..7945551
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392625.1 → NP_001379147.1  Transport and Golgi organization protein 1 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22666
      Conserved Domains (1) summary
      pfam09728
      Location:18 → 321
      Taxilin; Myosin-like coiled-coil protein
    Nucleotide Protein
    Heading Accession and Version

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