U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cyp-13A7 Putative cytochrome P450 CYP13A7 [ Caenorhabditis elegans ]

    Gene ID: 188362, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cyp-13A7
    Official Full Name
    Putative cytochrome P450 CYP13A7
    Primary source
    WormBase:WBGene00000372
    Locus tag
    CELE_T10B9.10
    See related
    AllianceGenome:WB:WBGene00000372
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in intestine. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; essential hypertension; familial Mediterranean fever; and leukemia (multiple). Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cyp-13A7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (9803620..9805513)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Putative cytochrome P450 CYP13A5 Neighboring gene Putative cytochrome P450 CYP13A6 Neighboring gene ncRNA Neighboring gene Putative cytochrome P450 CYP13A8 Neighboring gene Homeobox domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Toxicological assessment and underlying mechanisms of tetrabromobisphenol A exposure on the soil nematode Caenorhabditis elegans. Liu F, et al. Chemosphere, 2020 Mar. PMID 31704520
    2. Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression. Chakrapani BP, et al. J Biosci, 2008 Jun. PMID 18535361
    3. Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans. Thapa I, et al. Nucleic Acids Res, 2023 Mar 21. PMID 36250637, Free PMC Article
    4. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
    5. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Putative cytochrome P450 CYP13A7
    NP_496114.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9803620..9805513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063713.4 → NP_496114.1  Putative cytochrome P450 CYP13A7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496114.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q27519
      Conserved Domains (1) summary
      pfam00067
      Location:33 → 499
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q27519.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools