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    wdr-37 WD repeat-containing protein 37 [ Caenorhabditis elegans ]

    Gene ID: 175774, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wdr-37
    Official Full Name
    WD repeat-containing protein 37
    Primary source
    WormBase:WBGene00015470
    Locus tag
    CELE_C05D2.10
    See related
    AllianceGenome:WB:WBGene00015470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Human ortholog(s) of this gene implicated in neurooculocardiogenitourinary syndrome. Orthologous to human WDR37 (WD repeat domain 37). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See wdr-37 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (5597979..5600058, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cytochrome b-c1 complex subunit 1, mitochondrial;Peptidase M16 C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Cell death protein 6 Neighboring gene MADF domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    WD repeat-containing protein 37
    NP_001379621.1
    • Confirmed by transcript evidence
    NP_498204.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5597979..5600058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392101.1 → NP_001379621.1  WD repeat-containing protein 37 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95X41
      Conserved Domains (3) summary
      cd00200
      Location:129 → 390
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      PTZ00420
      Location:305 → 484
      PTZ00420; coronin; Provisional
      sd00039
      Location:184 → 276
      7WD40; WD40 repeat [structural motif]

    2. NM_065803.5 → NP_498204.1  WD repeat-containing protein 37 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498204.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95X42
      Conserved Domains (3) summary
      cd00200
      Location:131 → 392
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      PTZ00420
      Location:307 → 486
      PTZ00420; coronin; Provisional
      sd00039
      Location:186 → 278
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
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