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    tsp-10 Tetraspanin [ Caenorhabditis elegans ]

    Gene ID: 192063, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tsp-10
    Official Full Name
    Tetraspanin
    Primary source
    WormBase:WBGene00006636
    Locus tag
    CELE_T14B4.4
    See related
    AllianceGenome:WB:WBGene00006636
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tsp-10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (6718586..6720269)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Transmembrane protein Neighboring gene ncRNA Neighboring gene ANAPC4_WD40 domain-containing protein;DPPIV_N domain-containing protein Neighboring gene tRNA-Leu Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tetraspanin
    NP_001040805.1
    • Confirmed by transcript evidence
    NP_001040806.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6718586..6720269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047340.5 → NP_001040805.1  Tetraspanin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040805.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYX1
      Conserved Domains (2) summary
      cd03127
      Location:112 → 211
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:50 → 232
      Tetraspannin; Tetraspanin family

    2. NM_001047341.4 → NP_001040806.1  Tetraspanin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040806.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B1Q241
      Conserved Domains (2) summary
      cd03127
      Location:54 → 153
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:2 → 174
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version

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