Y25C1A.13 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y25C1A.13
Official Full Name: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
Primary source: WormBase:WBGene00021296
Locus tag: CELE_Y25C1A.13
See related: AllianceGenome:WB:WBGene00021296
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Is expressed in intestine. Orthologous to human ECH1 (enoyl-CoA hydratase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Y25C1A.13 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 4

Sequence:: Chromosome: II; NC_003280.10 (3109365..3111247, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y25C1A.13 (e-PCR)
- UniSTS:318932

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

NP_494448.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

3109365..3111247 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_062047.4 → NP_494448.1 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_494448.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9TYL2

Conserved Domains (1) summary

cl23717
Location:35 → 296

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...