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    T07F12.4 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180763, updated on 9-Dec-2024

    Summary

    Official Symbol
    T07F12.4
    Official Full Name
    Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00020324
    Locus tag
    CELE_T07F12.4
    See related
    AllianceGenome:WB:WBGene00020324
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including axon extension; macroautophagy; and regulation of autophagy. Predicted to be active in autophagosome; cytosol; and phagophore assembly site membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See T07F12.4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (4896602..4900801, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene PA domain-containing protein Neighboring gene Steroid-phosphate phosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RAB6-interacting golgin;Ras-associating domain-containing protein Neighboring gene Intermediate filament protein ifa-4

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in axon extension IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in piecemeal microautophagy of the nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of autophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in reticulophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in autophagosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in phagophore assembly site membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Protein kinase domain-containing protein
    NP_001368727.1
    • Confirmed by transcript evidence
    NP_001380246.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4896602..4900801 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392768.1NP_001380246.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A3P6MYF5
      Conserved Domains (1) summary
      smart00220
      Location:42292
      S_TKc; Serine/Threonine protein kinases, catalytic domain
    2. NM_001380955.1NP_001368727.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A3P6NNZ8
      Conserved Domains (1) summary
      smart00220
      Location:66316
      S_TKc; Serine/Threonine protein kinases, catalytic domain