nhr-199 Nuclear hormone receptor family member nhr-199 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: nhr-199
Official Full Name: Nuclear hormone receptor family member nhr-199
Primary source: WormBase:WBGene00010604
Locus tag: CELE_K06B4.10
See related: AllianceGenome:WB:WBGene00010604
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-199 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 4

Sequence:: Chromosome: V; NC_003283.11 (15698528..15699899, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

K06B4.10 (e-PCR)
- UniSTS:321564

K06B4.11 (e-PCR)
- UniSTS:311434

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Nuclear hormone receptor family member nhr-199

NP_506905.1

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

15698528..15699899 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074504.1 → NP_506905.1 Nuclear hormone receptor family member nhr-199 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506905.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O17934

Conserved Domains (2) summary

pfam00104
Location:155 → 344

Hormone_recep; Ligand-binding domain of nuclear hormone receptor

cl02596
Location:23 → 114

NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers