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    pqn-21 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172398, updated on 2-Nov-2024

    Summary

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    Official Symbol
    pqn-21
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00004111
    Locus tag
    CELE_C37A2.5
    See related
    AllianceGenome:WB:WBGene00004111
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including body wall musculature; intestine; spermatheca; tail; and ventral nerve cord. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See pqn-21 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    13
    Sequence:
    Chromosome: I; NC_003279.8 (6773973..6780151, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene BPH_3 domain-containing protein Neighboring gene Protein unc-87 Neighboring gene ncRNA Neighboring gene tRNA-Cys Neighboring gene G1/S-specific cyclin-E Neighboring gene medium-chain acyl-CoA dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-specific monitoring of protein synthesis in vivo. Kourtis N, et al. PLoS One, 2009. PMID 19234598, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_001021029.1
    • Confirmed by transcript evidence
    NP_001293280.1
    • Partially confirmed by transcript evidence
    NP_001293281.1
    • Confirmed by transcript evidence
    NP_491940.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6773973..6780151 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001025858.4 → NP_001021029.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021029.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EF29

    2. NM_059539.6 → NP_491940.2  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491940.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZ82

    3. NM_001306351.3 → NP_001293280.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293280.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6F562

    4. NM_001306352.3 → NP_001293281.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293281.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6FD15
    Nucleotide Protein
    Heading Accession and Version

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