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    Y71H2AM.3 E3 ubiquitin-protein ligase E3D [ Caenorhabditis elegans ]

    Gene ID: 190606, updated on 9-Dec-2024

    Summary

    Official Symbol
    Y71H2AM.3
    Official Full Name
    E3 ubiquitin-protein ligase E3D
    Primary source
    WormBase:WBGene00022168
    Locus tag
    CELE_Y71H2AM.3
    See related
    AllianceGenome:WB:WBGene00022168
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cyclin binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Orthologous to human UBE3D (ubiquitin protein ligase E3D). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Y71H2AM.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (2805430..2811778)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Potassium channel domain-containing protein Neighboring gene Peptidase C1A papain C-terminal domain-containing protein Neighboring gene Elongation factor Tu, mitochondrial Neighboring gene Phosphatidylinositol-4,5-bisphosphate 4-phosphatase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cyclin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein autoubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein monoubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase E3D
    NP_497622.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2805430..2811778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065221.3NP_497622.2  E3 ubiquitin-protein ligase E3D [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497622.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2AAC0
      Conserved Domains (1) summary
      cl19900
      Location:201467
      HECT_2; HECT-like Ubiquitin-conjugating enzyme (E2)-binding