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    K07H8.9 K Homology domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177620, updated on 9-Dec-2024

    Summary

    Official Symbol
    K07H8.9
    Official Full Name
    K Homology domain-containing protein
    Primary source
    WormBase:WBGene00019509
    Locus tag
    CELE_K07H8.9
    See related
    AllianceGenome:WB:WBGene00019509
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See K07H8.9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (8285175..8286476, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Nucleolin homolog 1 Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    K Homology domain-containing protein
    NP_501390.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8285175..8286476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068989.7NP_501390.1  K Homology domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501390.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45180
      Conserved Domains (1) summary
      cd02395
      Location:122245
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...