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    bcf-1 bacterial colonization factor [ Caenorhabditis elegans ]

    Gene ID: 3564957, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bcf-1
    Official Full Name
    bacterial colonization factor
    Primary source
    WormBase:WBGene00019017
    Locus tag
    CELE_F57F4.4
    See related
    AllianceGenome:WB:WBGene00019017
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in membrane raft. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bcf-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (6401379..6408783, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Filaggrin-2-like Neighboring gene HotDog ACOT-type domain-containing protein Neighboring gene ET module Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. f57f4.4p::gfp as a fluorescent reporter for analysis of the C. elegans response to bacterial infection. Julien-Gau I, et al. Dev Comp Immunol, 2014 Feb. PMID 24012871
    2. Bacterial peptidoglycan acts as a digestive signal mediating host adaptation to diverse food resources in C. elegans. Hao F, et al. Nat Commun, 2024 Apr 16. PMID 38627398, Free PMC Article
    3. Analysis of GPI-anchored proteins involved in germline stem cell proliferation in the Caenorhabditis elegans germline stem cell niche. Rikitake M, et al. J Biochem, 2020 Dec 26. PMID 32844210
    4. Galectin LEC-6 interacts with glycoprotein F57F4.4 to cooperatively regulate the growth of Caenorhabditis elegans. Takeuchi T, et al. Biol Pharm Bull, 2011. PMID 21720028
    5. N-glycosylated intestinal protein BCF-1 shapes microbial colonization by binding bacteria via its fimbrial protein. He Y, et al. Cell Rep, 2023 Jan 31. PMID 36662624

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. f57f4.4 expression is specifically induced in the intestine upon bacterial infections, but not in response to abiotic stress.
      Title: f57f4.4p::gfp as a fluorescent reporter for analysis of the C. elegans response to bacterial infection.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane raft HDA PubMed 

    General protein information

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    Preferred Names
    bacterial colonization factor
    NP_504627.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class bcf

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6401379..6408783 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072226.9 → NP_504627.1  bacterial colonization factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504627.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q94247
      Conserved Domains (1) summary
      pfam01684
      Location:1401 → 1480
      ET; ET module
    Nucleotide Protein
    Heading Accession and Version

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