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    rsy-1 Arginine/serine-rich protein PNISR [ Caenorhabditis elegans ]

    Gene ID: 173015, updated on 2-Nov-2024

    Summary

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    Official Symbol
    rsy-1
    Official Full Name
    Arginine/serine-rich protein PNISR
    Primary source
    WormBase:WBGene00013177
    Locus tag
    CELE_Y53H1A.1
    See related
    AllianceGenome:WB:WBGene00013177
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in nucleus and presynaptic active zone. Is expressed in neurons. Orthologous to human PNISR (PNN interacting serine and arginine rich protein). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See rsy-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (11216118..11221995, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Zinc finger protein ztf-6 Neighboring gene INSulin related Neighboring gene Ubiquitin-like domain-containing protein Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene Nuclear transcription factor Y subunit nfya-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Intramolecular regulation of presynaptic scaffold protein SYD-2/liprin-α. Chia PH, et al. Mol Cell Neurosci, 2013 Sep. PMID 23541703, Free PMC Article
    2. RSY-1 is a local inhibitor of presynaptic assembly in C. elegans. Patel MR, et al. Science, 2009 Mar 13. PMID 19286562, Free PMC Article
    3. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
    4. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in presynaptic active zone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in presynaptic active zone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Arginine/serine-rich protein PNISR
    NP_001122545.2
    • Confirmed by transcript evidence
    NP_492878.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11216118..11221995 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060477.5 → NP_492878.2  Arginine/serine-rich protein PNISR [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492878.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U252
      Conserved Domains (1) summary
      pfam15996
      Location:264 → 405
      PNISR; Arginine/serine-rich protein PNISR

    2. NM_001129073.4 → NP_001122545.2  Arginine/serine-rich protein PNISR [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122545.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8XQ35
      Conserved Domains (1) summary
      pfam15996
      Location:264 → 405
      PNISR; Arginine/serine-rich protein PNISR
    Nucleotide Protein
    Heading Accession and Version

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