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    hmg-1.1 HMG box domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175081, updated on 14-Nov-2024

    Summary

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    Official Symbol
    hmg-1.1
    Official Full Name
    HMG box domain-containing protein
    Primary source
    WormBase:WBGene00001971
    Locus tag
    CELE_Y48B6A.14
    See related
    AllianceGenome:WB:WBGene00001971
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription cis-regulatory region binding activity. Predicted to be located in mitochondrion and nucleus. Is expressed in several structures, including pharynx; ventral nerve cord; and vulva. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See hmg-1.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (14250695..14251450)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Coiled-coil domain-containing protein 25 Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PLP-1 binds nematode double-stranded telomeric DNA. Im SH, et al. Mol Cells, 2005 Oct 31. PMID 16267406
    2. Mitochondrial SKN-1/Nrf mediates a conserved starvation response. Paek J, et al. Cell Metab, 2012 Oct 3. PMID 23040073, Free PMC Article
    3. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB, et al. PLoS Biol, 2012. PMID 22927794, Free PMC Article
    4. Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. Hammerquist AM, et al. Sci Rep, 2020 Nov 9. PMID 33168938, Free PMC Article
    5. Stable-isotope labeling with amino acids in nematodes. Larance M, et al. Nat Methods, 2011 Aug 28. PMID 21874007, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding, bending IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HMG box domain-containing protein
    NP_001370073.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      14250695..14251450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383989.2 → NP_001370073.1  HMG box domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFV4
      Conserved Domains (1) summary
      cd01390
      Location:28 → 89
      HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
    Nucleotide Protein
    Heading Accession and Version

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