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    K08B12.3 Haloacid dehalogenase-like hydrolase domain-containing protein 2 [ Caenorhabditis elegans ]

    Gene ID: 187136, updated on 9-Dec-2024

    Summary

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    Official Symbol
    K08B12.3
    Official Full Name
    Haloacid dehalogenase-like hydrolase domain-containing protein 2
    Primary source
    WormBase:WBGene00019522
    Locus tag
    CELE_K08B12.3
    See related
    AllianceGenome:WB:WBGene00019522
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human HDHD2 (haloacid dehalogenase like hydrolase domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See K08B12.3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (6235176..6237734)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Haloacid dehalogenase-like hydrolase domain-containing protein 2
    NP_504597.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6235176..6237734
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072196.3 → NP_504597.1  Haloacid dehalogenase-like hydrolase domain-containing protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504597.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01581
      Conserved Domains (3) summary
      TIGR01458
      Location:4 → 252
      HAD-SF-IIA-hyp3; HAD-superfamily subfamily IIA hydrolase, TIGR01458
      pfam13242
      Location:173 → 245
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:7 → 100
      Hydrolase_6; Haloacid dehalogenase-like hydrolase
    Nucleotide Protein
    Heading Accession and Version

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