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    nadk-2 NAD kinase 2, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 174846, updated on 2-Nov-2024

    Summary

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    Official Symbol
    nadk-2
    Official Full Name
    NAD kinase 2, mitochondrial
    Primary source
    WormBase:WBGene00012463
    Locus tag
    CELE_Y17G7B.10
    See related
    AllianceGenome:WB:WBGene00012463
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable NAD+ kinase activity. Predicted to be involved in NAD metabolic process. Predicted to be active in mitochondrion. Orthologous to human NADK2 (NAD kinase 2, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See nadk-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (12049583..12059866)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Inositol-pentakisphosphate 2-kinase Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene Arrestin C-terminal-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NAD+ kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables NAD+ kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphotransferase activity, alcohol group as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in NAD metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in NAD metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in NADP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NAD kinase 2, mitochondrial
    NP_496565.2
    • Confirmed by transcript evidence
    NP_496566.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12049583..12059866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064164.7 → NP_496565.2  NAD kinase 2, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496565.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXI6
      Conserved Domains (1) summary
      cl01255
      Location:71 → 305
      DAGK_cat; Diacylglycerol kinase catalytic domain

    2. NM_064165.7 → NP_496566.1  NAD kinase 2, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496566.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXI5
      Conserved Domains (1) summary
      cl01255
      Location:132 → 366
      DAGK_cat; Diacylglycerol kinase catalytic domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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