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    elmd-1 ELMO domain-containing protein;ELMO domain-containing protein C56G7.3 [ Caenorhabditis elegans ]

    Gene ID: 175439, updated on 2-Nov-2024

    Summary

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    Official Symbol
    elmd-1
    Official Full Name
    ELMO domain-containing protein;ELMO domain-containing protein C56G7.3
    Primary source
    WormBase:WBGene00008348
    Locus tag
    CELE_C56G7.3
    See related
    AllianceGenome:WB:WBGene00008348
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in ciliated neurons. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness and autosomal recessive nonsyndromic deafness 88. Orthologous to human ELMOD3 (ELMO domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See elmd-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (3389919..3392525)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene E3 ubiquitin-protein ligase hecw-1 Neighboring gene tRNA-Lys Neighboring gene ncRNA Neighboring gene Myosin regulatory light chain Neighboring gene Conserved regulator of innate immunity protein 3 Neighboring gene Pre-mRNA cleavage complex subunit Clp1 C-terminal domain-containing protein;Protein clpf-1 Neighboring gene Nuclear Pore complex Protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium. Cevik S, et al. Life Sci Alliance, 2023 Aug. PMID 37208194, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    ELMO domain-containing protein;ELMO domain-containing protein C56G7.3
    NP_001299864.1
    • Confirmed by transcript evidence
    NP_001299865.1
    • Confirmed by transcript evidence
    NP_497699.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3389919..3392525
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065298.5 → NP_497699.1  ELMO domain-containing protein C56G7.3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497699.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09292
      Conserved Domains (1) summary
      pfam04727
      Location:127 → 284
      ELMO_CED12; ELMO/CED-12 family

    2. NM_001312935.3 → NP_001299864.1  ELMO domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AU43
      Conserved Domains (1) summary
      pfam04727
      Location:90 → 248
      ELMO_CED12; ELMO/CED-12 family

    3. NM_001312936.3 → NP_001299865.1  ELMO domain-containing protein C56G7.3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AR87
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09292.2

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