B0280.9 U3 small nucleolar RNA-associated protein 18 homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: B0280.9
Official Full Name: U3 small nucleolar RNA-associated protein 18 homolog
Primary source: WormBase:WBGene00015104
Locus tag: CELE_B0280.9
See related: AllianceGenome:WB:WBGene00015104
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Orthologous to human UTP18 (UTP18 small subunit processome component). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See B0280.9 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 8

Sequence:: Chromosome: III; NC_003281.10 (7120905..7122895, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0280.9 (e-PCR)
- UniSTS:308839

B0280.3 (e-PCR)
- UniSTS:308364

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Pwp2p-containing subcomplex of 90S preribosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: U3 small nucleolar RNA-associated protein 18 homolog

NP_498555.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7120905..7122895 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066154.6 → NP_498555.1 U3 small nucleolar RNA-associated protein 18 homolog [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498555.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P42000

Conserved Domains (3) summary

COG2319
Location:66 → 424

WD40; WD40 repeat [General function prediction only]

sd00039
Location:258 → 296

7WD40; WD40 repeat [structural motif]

cl02567
Location:167 → 423

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...