trd-1 Tetratricopeptide repeat-containing protein trd-1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: trd-1
Official Full Name: Tetratricopeptide repeat-containing protein trd-1
Primary source: WormBase:WBGene00020600
Locus tag: CELE_T20B12.1
See related: AllianceGenome:WB:WBGene00020600
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in cell differentiation. Predicted to be located in cytoplasm. Is expressed in gonad; gonadal primordium; seam cell; and vulval precursor cell. Orthologous to human TTC27 (tetratricopeptide repeat domain 27). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See trd-1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 8

Sequence:: Chromosome: III; NC_003281.10 (7386229..7391135)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

regulates cell fate in the developing germ line and epidermis
Title: The C. elegans TPR Containing Protein, TRD-1, Regulates Cell Fate Choice in the Developing Germ Line and Epidermis.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T20B12.1 (e-PCR)
- UniSTS:310897

T20B12.2 (e-PCR)
- UniSTS:310898

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Tetratricopeptide repeat-containing protein trd-1

NP_498636.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

7386229..7391135

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066235.7 → NP_498636.2 Tetratricopeptide repeat-containing protein trd-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498636.2

Status: REVIEWED

UniProtKB/Swiss-Prot

P41842

Conserved Domains (3) summary

COG0457
Location:368 → 631

TPR; Tetratricopeptide (TPR) repeat [General function prediction only]

COG3063
Location:399 → 517

PilF; Tfp pilus assembly protein PilF [Cell motility, Extracellular structures]

sd00006
Location:451 → 479

TPR; TPR repeat [structural motif]