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    mrps-12 Small ribosomal subunit protein uS12m [ Caenorhabditis elegans ]

    Gene ID: 180368, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrps-12
    Official Full Name
    Small ribosomal subunit protein uS12m
    Primary source
    WormBase:WBGene00011391
    Locus tag
    CELE_T03D8.2
    See related
    AllianceGenome:WB:WBGene00011391
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in ribosome. Orthologous to human MRPS12 (mitochondrial ribosomal protein S12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mrps-12 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (20838080..20838768)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ground-like domain-containing protein Neighboring gene Neuroendocrine protein 7B2 Neighboring gene Numb-related protein 1;PID domain-containing protein Neighboring gene Ribosomal RNA-processing protein 42 Neighboring gene Sugar phosphate phosphatase Neighboring gene peptidylprolyl isomerase Neighboring gene C-type lectin domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. Suzuki T, et al. J Biol Chem, 2001 Aug 31. PMID 11402041
    2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Small ribosomal subunit protein uS12m
    NP_508023.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      20838080..20838768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075622.7 → NP_508023.1  Small ribosomal subunit protein uS12m [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508023.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XTY5
      Conserved Domains (1) summary
      cd03368
      Location:46 → 156
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...
    Nucleotide Protein
    Heading Accession and Version

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