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    trmt-10A tRNA methyltransferase 10 homolog A [ Caenorhabditis elegans ]

    Gene ID: 177847, updated on 2-Nov-2024

    Summary

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    Official Symbol
    trmt-10A
    Official Full Name
    tRNA methyltransferase 10 homolog A
    Primary source
    WormBase:WBGene00009131
    Locus tag
    CELE_F25H8.1
    See related
    AllianceGenome:WB:WBGene00009131
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable tRNA binding activity. Predicted to be involved in tRNA N1-guanine methylation. Predicted to be active in nucleoplasm. Orthologous to human TRMT10A (tRNA methyltransferase 10A). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See trmt-10A in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (9930896..9932213, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Zinc finger BED domain-containing protein 3 Neighboring gene ncRNA Neighboring gene Dauer Up-Regulated Neighboring gene H/ACA ribonucleoprotein complex non-core subunit NAF1 Neighboring gene Uncharacterized protein Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Domain selection combined with improved cloning strategy for high throughput expression of higher eukaryotic proteins. Chen Y, et al. BMC Biotechnol, 2007 Jul 30. PMID 17663785, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (guanosine(9)-N1)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA N1-guanine methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tRNA methyltransferase 10 homolog A
    NP_001122773.1
    • Confirmed by transcript evidence
    NP_501789.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9930896..9932213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129301.3 → NP_001122773.1  tRNA methyltransferase 10 homolog A [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122773.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYS8
      Conserved Domains (1) summary
      cd18101
      Location:86 → 259
      Trm10euk_A; eukaryotic tRNA m1G9 methyltransferase Trm10 homolog A

    2. NM_069388.7 → NP_501789.1  tRNA methyltransferase 10 homolog A [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501789.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19789
      Conserved Domains (1) summary
      cd18101
      Location:87 → 260
      Trm10euk_A; eukaryotic tRNA m1G9 methyltransferase Trm10 homolog A
    Nucleotide Protein
    Heading Accession and Version

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