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    T28F4.3 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

    Gene ID: 189059, updated on 2-Nov-2024

    Summary

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    Official Symbol
    T28F4.3
    Official Full Name
    Protein-tyrosine phosphatase
    Primary source
    WormBase:WBGene00012138
    Locus tag
    CELE_T28F4.3
    See related
    AllianceGenome:WB:WBGene00012138
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance and signal transduction. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See T28F4.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (7484062..7486293, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Degenerin-like protein asic-2 Neighboring gene Inverted formin-2;PUM-HD domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine phosphatase
    NP_492100.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7484062..7486293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059699.3 → NP_492100.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492100.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22852
      Conserved Domains (2) summary
      smart00194
      Location:58 → 312
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:86 → 312
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    Nucleotide Protein
    Heading Accession and Version

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