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    ctg-1 Protein ctg-1 [ Caenorhabditis elegans ]

    Gene ID: 172431, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ctg-1
    Official Full Name
    Protein ctg-1
    Primary source
    WormBase:WBGene00010370
    Locus tag
    CELE_H06O01.3
    See related
    AllianceGenome:WB:WBGene00010370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in regulation of basement membrane organization. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to several human genes including SEC14L2 (SEC14 like lipid binding 2); SEC14L3 (SEC14 like lipid binding 3); and SEC14L4 (SEC14 like lipid binding 4). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ctg-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (7005443..7009200)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene AbLIM_anchor domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene DNA helicase Neighboring gene ncRNA Neighboring gene Protein disulfide-isomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling. McClatchey ST, et al. Elife, 2016 Sep 23. PMID 27661254, Free PMC Article
    2. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of basement membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein ctg-1
    NP_001263451.1
    • Confirmed by transcript evidence
    NP_001263452.1
    • Confirmed by transcript evidence
    NP_491993.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7005443..7009200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059592.6 → NP_491993.1  Protein ctg-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491993.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      K8ES75, K8F7T8, O17907
      Conserved Domains (1) summary
      smart00516
      Location:73 → 244
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)

    2. NM_001276522.3 → NP_001263451.1  Protein ctg-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263451.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8ES75
      Conserved Domains (1) summary
      smart00516
      Location:13 → 149
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)

    3. NM_001276523.3 → NP_001263452.1  Protein ctg-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263452.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8F7T8
      Conserved Domains (1) summary
      smart00516
      Location:1 → 100
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O17907.2

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