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    W05B10.4 Ras-associating domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179736, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W05B10.4
    Official Full Name
    Ras-associating domain-containing protein
    Primary source
    WormBase:WBGene00012279
    Locus tag
    CELE_W05B10.4
    See related
    AllianceGenome:WB:WBGene00012279
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in positive regulation of epidermal growth factor receptor signaling pathway and positive regulation of fibroblast growth factor receptor signaling pathway. Is expressed in several structures, including P5.ppal; P5.ppp; P7.paa; pharynx; and vulval cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W05B10.4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (12668226..12669689)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene tRNA-Val Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
    2. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in positive regulation of epidermal growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of fibroblast growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ras-associating domain-containing protein
    NP_506166.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12668226..12669689
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073765.6 → NP_506166.1  Ras-associating domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506166.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91575
      Conserved Domains (2) summary
      pfam00788
      Location:70 → 167
      RA; Ras association (RalGDS/AF-6) domain
      cl00155
      Location:169 → 247
      UBQ; Ubiquitin-like proteins
    Nucleotide Protein
    Heading Accession and Version

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