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    twk-9 Potassium channel domain-containing protein;TWiK family of potassium channels protein 9 [ Caenorhabditis elegans ]

    Gene ID: 177803, updated on 2-Nov-2024

    Summary

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    Official Symbol
    twk-9
    Official Full Name
    Potassium channel domain-containing protein;TWiK family of potassium channels protein 9
    Primary source
    WormBase:WBGene00006664
    Locus tag
    CELE_ZK1251.8
    See related
    AllianceGenome:WB:WBGene00006664
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See twk-9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    12
    Sequence:
    Chromosome: IV; NC_003282.8 (9693174..9697005)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Major sperm protein 10/36/56/76 Neighboring gene SKN-1 Dependent Zygotic transcript Neighboring gene DDB1- and CUL4-associated factor homolog 1 Neighboring gene ncRNA Neighboring gene DPH-type MB domain-containing protein;Diphthamide biosynthesis protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium ion leak channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Potassium channel domain-containing protein;TWiK family of potassium channels protein 9
    NP_001294002.1
    • Confirmed by transcript evidence
    NP_501724.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9693174..9697005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069323.3 → NP_501724.2  TWiK family of potassium channels protein 9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501724.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23435
      Conserved Domains (1) summary
      pfam07885
      Location:159 → 217
      Ion_trans_2; Ion channel

    2. NM_001307073.3 → NP_001294002.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294002.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AD18
      Conserved Domains (1) summary
      pfam07885
      Location:159 → 217
      Ion_trans_2; Ion channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q23435.2

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