U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    oxa-1 Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173207, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    oxa-1
    Official Full Name
    Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00007215
    Locus tag
    CELE_C01A2.3
    See related
    AllianceGenome:WB:WBGene00007215
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable membrane insertase activity. Predicted to be involved in protein insertion into mitochondrial inner membrane from matrix. Located in mitochondrion. Is expressed in body wall musculature and pharyngeal muscle cell. Orthologous to human OXA1L (OXA1L mitochondrial inner membrane protein). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See oxa-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (13387819..13391205)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene WWE domain-containing protein Neighboring gene Replication termination factor 2 Neighboring gene Charged multivesicular body protein 2b Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The SFT-1 and OXA-1 respiratory chain complex assembly factors influence lifespan by distinct mechanisms in C. elegans. Maxwell S, et al. Longev Healthspan, 2013 May 8. PMID 24472117, Free PMC Article
    2. Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Simmer F, et al. Curr Biol, 2002 Aug 6. PMID 12176360
    3. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables membrane insertase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables membrane insertase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein insertion into mitochondrial inner membrane from matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein
    NP_493356.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      13387819..13391205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060955.8 → NP_493356.2  Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493356.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O02207
      Conserved Domains (1) summary
      cl00489
      Location:106 → 296
      60KD_IMP; 60Kd inner membrane protein
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous