U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    scm-1 Secretory carrier-associated membrane protein [ Caenorhabditis elegans ]

    Gene ID: 171756, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    scm-1
    Official Full Name
    Secretory carrier-associated membrane protein
    Primary source
    WormBase:WBGene00004743
    Locus tag
    CELE_M01D7.2
    See related
    AllianceGenome:WB:WBGene00004743
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein transport. Located in cytoplasmic vesicle. Is expressed in amphid neurons; coelomocyte; and spermatheca. Orthologous to several human genes including SCAMP1 (secretory carrier membrane protein 1) and SCAMP2 (secretory carrier membrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See scm-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (1862607..1872306, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene 7TM_GPCR_Srx domain-containing protein Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Tubby C-terminal domain-containing protein Neighboring gene AB hydrolase-1 domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in Caenorhabditis elegans. Abraham C, et al. Proc Natl Acad Sci U S A, 2006 May 23. PMID 16698939, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in recycling endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in trans-Golgi network membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Secretory carrier-associated membrane protein
    NP_001293354.1
    • Confirmed by transcript evidence
    NP_001293355.1
    • Confirmed by transcript evidence
    NP_490911.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1862607..1872306 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058510.8 → NP_490911.1  Secretory carrier-associated membrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490911.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EED5
      Conserved Domains (1) summary
      pfam04144
      Location:116 → 289
      SCAMP; SCAMP family

    2. NM_001306425.3 → NP_001293354.1  Secretory carrier-associated membrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293354.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5M5X6
      Conserved Domains (1) summary
      pfam04144
      Location:50 → 224
      SCAMP; SCAMP family

    3. NM_001306426.3 → NP_001293355.1  Secretory carrier-associated membrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293355.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5M914
      Conserved Domains (1) summary
      pfam04144
      Location:2 → 134
      SCAMP; SCAMP family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous