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    ent-1 Equilibrative nucleoside transporter 3 [ Caenorhabditis elegans ]

    Gene ID: 178097, updated on 2-Nov-2024

    Summary

    Official Symbol
    ent-1
    Official Full Name
    Equilibrative nucleoside transporter 3
    Primary source
    WormBase:WBGene00001320
    Locus tag
    CELE_ZK809.4
    See related
    AllianceGenome:WB:WBGene00001320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Located in plasma membrane. Is expressed in intestine; isthmus; metacorpus; procorpus; and terminal bulb. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See ent-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (11653417..11655470, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Tafazzin family protein Neighboring gene ncRNA Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cilia- and flagella-associated protein 157

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleoside transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleoside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in nucleoside transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nucleoside transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Equilibrative nucleoside transporter 3
    NP_001255573.1
    • Confirmed by transcript evidence
    NP_001255574.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11653417..11655470 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268644.2NP_001255573.1  Equilibrative nucleoside transporter 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255573.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDJ3
      Conserved Domains (1) summary
      cl15430
      Location:151440
      Nucleoside_tran; Nucleoside transporter
    2. NM_001268645.3NP_001255574.1  Equilibrative nucleoside transporter 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255574.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F5GU99
      Conserved Domains (1) summary
      cl15430
      Location:1124
      Nucleoside_tran; Nucleoside transporter