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    egl-1 Programmed cell death activator egl-1 [ Caenorhabditis elegans ]

    Gene ID: 179943, updated on 9-Dec-2024

    Summary

    Official Symbol
    egl-1
    Official Full Name
    Programmed cell death activator egl-1
    Primary source
    WormBase:WBGene00001170
    Locus tag
    CELE_F23B12.9
    See related
    AllianceGenome:WB:WBGene00001170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in several processes, including actin filament depolymerization; defense response to Gram-negative bacterium; and positive regulation of cellular component organization. Located in cytosol; mitochondrion; and presynapse. Is expressed in several structures, including ABalappaapp; ABaraapapaad; HSN; URX; and proctodeal cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See egl-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (14431308..14432359, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Serine/threonine-protein phosphatase Neighboring gene pseudo Neighboring gene Reelin domain-containing protein;ShKT domain-containing protein Neighboring gene ncRNA

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytosol PubMed 
    located_in intracellular membrane-bounded organelle PubMed 
    located_in mitochondrion PubMed 
    located_in presynapse PubMed 
    located_in synapse  

    General protein information

    Preferred Names
    Programmed cell death activator egl-1
    NP_506575.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14431308..14432359 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074174.6 → NP_506575.2  Programmed cell death activator egl-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506575.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O61667, Q7JLC9
      Conserved Domains (1) summary
      pfam11430
      Location:67 → 86
      EGL-1; Programmed cell death activator EGL-1
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