JC8.7 Zinc finger, CCHC-type [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: JC8.7
Official Full Name: Zinc finger, CCHC-type
Primary source: WormBase:WBGene00010439
Locus tag: CELE_JC8.7
See related: AllianceGenome:WB:WBGene00010439
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable histone binding activity and poly-ADP-D-ribose binding activity. Predicted to be involved in DNA repair-dependent chromatin remodeling and double-strand break repair. Predicted to be located in chromosome. Predicted to be active in nucleus. Orthologous to human HPF1 (histone PARylation factor 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See JC8.7 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 4

Sequence:: Chromosome: IV; NC_003282.8 (13247261..13250699)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

JC8.7 (e-PCR)
- UniSTS:313220

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables histone binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone binding	IEA Inferred from Electronic Annotation more info
enables poly-ADP-D-ribose binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA damage response	IEA Inferred from Electronic Annotation more info
involved_in DNA repair-dependent chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in double-strand break repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of protein ADP-ribosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Zinc finger, CCHC-type

NP_001255715.1

Confirmed by transcript evidence

NP_001255716.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

13247261..13250699

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001268786.4 → NP_001255715.1 Zinc finger, CCHC-type [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255715.1

Status: REVIEWED

UniProtKB/TrEMBL

O62291

Conserved Domains (1) summary

pfam10228
Location:69 → 318

DUF2228; uncharacterized conserved protein (DUF2228)
NM_001268787.3 → NP_001255716.1 Zinc finger, CCHC-type [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255716.1

Status: REVIEWED

UniProtKB/TrEMBL

D3YT79

Conserved Domains (1) summary

pfam10228
Location:1 → 230

DUF2228; uncharacterized conserved protein (DUF2228)