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    ccdc-149 Coiled-coil domain-containing protein 149 [ Caenorhabditis elegans ]

    Gene ID: 185121, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ccdc-149
    Official Full Name
    Coiled-coil domain-containing protein 149
    Primary source
    WormBase:WBGene00009258
    Locus tag
    CELE_F29G6.2
    See related
    AllianceGenome:WB:WBGene00009258
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in ciliary base. Is expressed in neurons. Orthologous to human CCDC149 (coiled-coil domain containing 149). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ccdc-149 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (11509442..11511451, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene C-type LECtin Neighboring gene Kazal-like domain-containing protein Neighboring gene Protein kinase domain-containing protein;ZM domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Lakhina V, et al. Neuron, 2015 Jan 21. PMID 25611510, Free PMC Article
    2. Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. Jensen VL, et al. PLoS Genet, 2016 Dec. PMID 27930654, Free PMC Article
    3. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in ciliary base IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Coiled-coil domain-containing protein 149
    NP_509921.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      11509442..11511451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077520.3 → NP_509921.1  Coiled-coil domain-containing protein 149 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509921.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93635
      Conserved Domains (1) summary
      pfam09789
      Location:20 → 336
      DUF2353; Uncharacterized coiled-coil protein (DUF2353)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93635.1

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