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    K10C3.4 Transmembrane protein 98 [ Caenorhabditis elegans ]

    Gene ID: 187255, updated on 2-Nov-2024

    Summary

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    Official Symbol
    K10C3.4
    Official Full Name
    Transmembrane protein 98
    Primary source
    WormBase:WBGene00010731
    Locus tag
    CELE_K10C3.4
    See related
    AllianceGenome:WB:WBGene00010731
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in extracellular region and plasma membrane. Predicted to be active in endoplasmic reticulum. Is expressed in hermaphrodite distal tip cell; hypodermis; neurons; pharyngeal cell; and vulva. Human ortholog(s) of this gene implicated in nanophthalmos. Orthologous to human TMEM98 (transmembrane protein 98). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See K10C3.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (9853654..9863495)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Zwei Ig domain protein zig-1 Neighboring gene mRNA stability protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Tr-type G domain-containing protein Neighboring gene NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-49

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein 98
    NP_001251226.1
    • Confirmed by transcript evidence
    NP_001251227.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9853654..9863495
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001264297.3 → NP_001251226.1  Transmembrane protein 98 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251226.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45665

    2. NM_001264298.1 → NP_001251227.1  Transmembrane protein 98 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251227.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E9P8A0

    RNA

    1. NR_138503.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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