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    W07G1.1 Doublecortin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189278, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W07G1.1
    Official Full Name
    Doublecortin domain-containing protein
    Primary source
    WormBase:WBGene00012328
    Locus tag
    CELE_W07G1.1
    See related
    AllianceGenome:WB:WBGene00012328
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in intracellular signal transduction. Predicted to be active in microtubule and microtubule organizing center. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; dyslexia; nephronophthisis 19; and sclerosing cholangitis. Orthologous to several human genes including DCDC2 (doublecortin domain containing 2) and DCDC2C (doublecortin domain containing 2C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W07G1.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (13937995..13939631, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Doublecortin domain-containing protein
    NP_496917.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      13937995..13939631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064516.2 → NP_496917.2  Doublecortin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496917.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUK4
      Conserved Domains (1) summary
      cd01617
      Location:31 → 102
      DCX; Dublecortin-like domain structurally similar to a beta-grasp ubiquitin-like fold
    Nucleotide Protein
    Heading Accession and Version

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