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    F48E8.4 MRH domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185984, updated on 9-Dec-2024

    Summary

    Official Symbol
    F48E8.4
    Official Full Name
    MRH domain-containing protein
    Primary source
    WormBase:WBGene00018611
    Locus tag
    CELE_F48E8.4
    See related
    AllianceGenome:WB:WBGene00018611
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in retrograde protein transport, ER to cytosol. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human OS9 (OS9 endoplasmic reticulum lectin). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F48E8.4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    14
    Sequence:
    Chromosome: III; NC_003281.10 (5453590..5460347)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Hsp20/alpha crystallin family protein Neighboring gene putative serine/threonine-protein phosphatase PP2A regulatory subunit Neighboring gene FAD-dependent oxidoreductase 2 FAD binding domain-containing protein Neighboring gene E2F-associated phosphoprotein Neighboring gene Protein lon-1;SCP domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in ERAD pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde protein transport, ER to cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    MRH domain-containing protein
    NP_001367874.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5453590..5460347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379711.3NP_001367874.1  MRH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q09396
      Conserved Domains (1) summary
      pfam07915
      Location:122193
      PRKCSH; Glucosidase II beta subunit-like protein