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    ttm-2 Protein ttm-2 [ Caenorhabditis elegans ]

    Gene ID: 184995, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ttm-2
    Official Full Name
    Protein ttm-2
    Primary source
    WormBase:WBGene00017840
    Locus tag
    CELE_F26G1.4
    See related
    AllianceGenome:WB:WBGene00017840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in response to nematicide. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See ttm-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (4764159..4766384, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene DUF4316 domain-containing protein;Signal peptide protein Neighboring gene protein of unknown function DB domain-containing protein Neighboring gene protein of unknown function DB domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Huffman DL, et al. Proc Natl Acad Sci U S A, 2004 Jul 27. PMID 15256590, Free PMC Article
    2. Worms and flies as genetically tractable animal models to study host-pathogen interactions. Mylonakis E, et al. Infect Immun, 2005 Jul. PMID 15972468, Free PMC Article
    3. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to nematicide IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein ttm-2
    NP_494855.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4764159..4766384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062454.4 → NP_494855.1  Protein ttm-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494855.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q19829
      Conserved Domains (2) summary
      cl02844
      Location:231 → 326
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:7 → 149
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q19829.1

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