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    Y80D3A.8 Protein-tyrosine-phosphatase [ Caenorhabditis elegans ]

    Gene ID: 180237, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y80D3A.8
    Official Full Name
    Protein-tyrosine-phosphatase
    Primary source
    WormBase:WBGene00013586
    Locus tag
    CELE_Y80D3A.8
    See related
    AllianceGenome:WB:WBGene00013586
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y80D3A.8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (18940641..18946925)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene DUF833-domain-containing protein Neighboring gene C2H2-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine-phosphatase
    NP_507691.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      18940641..18946925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075290.4 → NP_507691.2  Protein-tyrosine-phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507691.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U1Q9
      Conserved Domains (5) summary
      smart00453
      Location:39 → 106
      WSN; Worm-specific (usually) N-terminal domain
      cd00047
      Location:1012 → 1243
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:1010 → 1241
      Y_phosphatase; Protein-tyrosine phosphatase
      pfam05672
      Location:897 → 947
      MAP7; MAP7 (E-MAP-115) family
      pfam12572
      Location:908 → 947
      DUF3752; Protein of unknown function (DUF3752)
    Nucleotide Protein
    Heading Accession and Version

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