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    taco-1 Transcriptional regulatory protein [ Caenorhabditis elegans ]

    Gene ID: 175191, updated on 9-Dec-2024

    Summary

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    Official Symbol
    taco-1
    Official Full Name
    Transcriptional regulatory protein
    Primary source
    WormBase:WBGene00021757
    Locus tag
    CELE_Y50D7A.9
    See related
    AllianceGenome:WB:WBGene00021757
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 8. Orthologous to human TACO1 (translational activator of cytochrome c oxidase I). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See taco-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (284117..289438)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein;phosphorylase kinase Neighboring gene DNA 5'-3' helicase Neighboring gene ncRNA Neighboring gene 30S ribosomal protein S15;Peptidase metallopeptidase domain-containing protein Neighboring gene DUF295 domain-containing protein;F-box domain-containing protein Neighboring gene ncRNA Neighboring gene Alkyldihydroxyacetonephosphate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
    2. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Transcriptional regulatory protein
    NP_497183.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      284117..289438
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064782.5 → NP_497183.1  Transcriptional regulatory protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497183.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q965T4
      Conserved Domains (1) summary
      pfam01709
      Location:45 → 281
      Transcrip_reg; Transcriptional regulator
    Nucleotide Protein
    Heading Accession and Version

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